US20110300149A1 - Ljungan virus - Google Patents Ljungan virus Download PDF Info Publication number US20110300149A1. US20110300149A1 US13/141,758 US200913141758A US2011300149A1 US 20110300149 A1 US20110300149 A1 US 20110300149A1 US 200913141758 A US200913141758 A US 200913141758A US 2011300149 A1 US2011300149 A1 US 2011300149A1

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Några sådana nyheter är att det farliga Ljunganviruset kan orsaka orienterarsjuka, graviditetsförgiftning, fosterdöd, missbildningar, SIDS och barndiabetes. Men svenska virusjägare är detta virus på spåren, och via media har vi fått rapporter om deras framsteg. Nu senast i SVT.

Ljungan Virus Replication in Cell Culture Jens-Ola Ekström School of Pure and Applied Natural Sciences University of Kalmar, Sweden, 2007 Akademisk avhandling som, för vinnande av doktorsexamen i biomedicinsk vetenskap vid Fakulteten för naturvetenskap och teknik vid Högskolan i Kalmar, Det är känt att Ljunganvirus kan orsaka diabetes, hjärtmuskel-inflammation, inflammation i det centrala nervsystemet och fosterskador hos sork och mus. Utbrott av sjukdomssymptom ser ut att utlösas av höga stressnivåer, i alla fall bland gnagare. Det är fortfarande oklart om Ljunganviruset kan infektera människa. Ljungan virus types 1 to 6 belong to the species Parechovirus B, genus Parechovirus.. The partial genome sequence of a virus isolated from bank voles (Clethrionomys glareolus) was originally determined by Niklasson et al. Ljunganvirus drabbar sorkar och andra gnagare. Det tillhör gruppen parechovirus, vars humana varianter drabbar oss alla någon gång under livet, i regel utan att ge allvarligare symtom.

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Replication of Ljungan virus in cultured cells normally induces a weak and delayed cytopathic effect compared to that of many other picornaviruses. However, efficiently replicating Ljungan virus variants may evolve during serial passages in cell culture. Ljungan virus (LV), a picornavirus, was discovered in the Swedish vole population after six clustered deaths from myocarditis were noted in orienteers between 1989 and 1992. Ljungan virus types 1 to 6 belong to the species Parechovirus B, genus Parechovirus.

Vilda smågnagare är kända  av T Bergström · 2008 — Ljungan virus present in intrauterine fetal death diagnosed by both immunohisto- chemistry and PCR. Birth Defects. Res A Clin Mol Teratol. 2009;85.

Dec 18, 2002 Ljungan virus inoculation of nondiabetic wild bank voles induced 1 diabetes in captured wild bank voles is associated with Ljungan virus.

Ljungan virus shows substantial differences in the capsid structure, indicating that a different capsid form could have an effect on genome encapsidation and thus play a role in the production of Ljungan virus was isolated in 1999 (Niklasson et al. 1999), and has subsequently been detected in many species of small rodents, especially voles (Arvicolinae; Johansson et al. 2003; Hauffe et al. 2010; Salisbury et al.

Ljungan virus

även svampproblematiken i Mörrumsån, Ljungan och Stockholms ström. Varken virus eller bakterier som går att odla fram gick att sätta i samband med 

Watch Queue Queue. Watch Queue Queue Ljungan virus är ett nyupptäckt virus och därför är kunskapen om viruset begränsad. För att öka vår förståelse om viruset så har arvsmassan för tre svenska isolat (87-012, 174F och 145SL) av Ljungan virus kartlagts (artikel IV). Denna studie visade att Ljungan virusets arvmassa har flera unika egenskaper. Ljungan virus cDNA. The Ljungan virus isolate 87-012 (23) was subcloned in the pCRII- TOPO vector (Life technologies, Grand Island, NY) to contain nucleotide posi-tions 301–2685 representing VP0 (VP2), VP3, and VP1(28). The resulting cDNA clone, pLV1, was verified by sequencing and used in coupled in vitro transcription translation to label Ljungan virus Download PDF Info Publication number US20110300149A1. US20110300149A1 US13/141,758 US200913141758A US2011300149A1 US 20110300149 A1 US20110300149 A1 US variation of Ljungan virus in bank voles (Myodes glareolus) in Fennoscandia.

Ljungan virus

Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children Anna-Lena Nilsson,1,2 Fariba Vaziri-Sani,2 Cecilia Andersson,2 Karin Larsson,3 Anneli Carlsson,2 Elisabeth Cedervall,4 Bjo¨rn Jo¨nsson,5 Jan Neiderud,6 Helena Elding Larsson,2 Sten-Anders Ivarsson,2 and A˚ke Lernmark2 Abstract Parechovirus is a genus of viruses in the family Picornaviridae.Humans, ferrets, and various rodents serve as natural hosts. The genus currently consists of six accepted species. Human parechoviruses may cause gastrointestinal or respiratory illness in infants, and have been implicated in cases of myocarditis and encephalitis. Read "Ljungan virus: A commentary on its association with fetal and infant morbidity and mortality in animals and humans, Birth Defects Research Part A" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Ljungan virus a novel pathogen : Effects on the pregnant female and her offspring Relationship Between Ljungan Virus Antibodies, HLA-DQ8, and Insulin Autoantibodies in Newly Diagnosed Type 1 Diabetes Children. Research output: Contribution to journal › Article In four of these Ljungan virus was found in the stillborn children as well. A control group of twenty women with normal pregnancies showed that each of their placentas was free from the virus.
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Ljungan virus

GenBank Sequence  23 Jun 2014 Chikungunya is a virus transmitted by Aedes aegypti and Aedes albopictus mosquitoes (the same mosquito species that transmit dengue). Ljungan virus. ▫ Animal.

… 2009-12-01 In April 2003, the (nearly) complete genome sequence of an American Ljungan virus was reported (Johansson et al., 2003; AF538689).
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Bank voles (Clethrionomys glareolus) kept in captivity develop diabetes mellitus to a significant extent. Also in wild bank voles, elevated blood glucose has been observed. A newly isolated picornavirus named Ljungan virus (LV) has been found in the pancreas of these bank voles. Moreover, LV infecti …

Ljungan virus (LV) has recently been associated with perinatal death in its natural rodent reservoir and also with developmental disorders of reproduction in laboratory mice. A strong epidemiological association has been found between small rodent abundance in Sweden and the incidence of intrauterine fetal death (IUFD) in humans. 2020-04-23 A pathogenic virusof the viral family which includes polioand hepatitis Awas isolated from a bank volenear the Ljungan river in the mid-1990s, and named Ljungan virus.


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Ljungan virus (LV) was discovered 20 years ago in Swedish bank voles (Myodes glareolus, previously referred to as Clethrionomys glareolus) during the search for an infectious agent causing lethal myocarditis in young athletes. To date, the genomes of four LV isolates, including the prototype 87-012 strain, have been characterized.

Vipendwa 21. Ljungan is a 322 kilometer long river in Sweden. and named Ljungan virus.